Issue Published Current Pharmaceutical Design Vol.22 issue 41
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Wednesday, December 28, 2016
Most Accessed Article: Dry Eye Disease: Present Challenges in the Management and Future Trends
Most Accessed Article: Dry Eye Disease: Present Challenges in the Management and Future Trends
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Wednesday, December 21, 2016
Thursday, December 15, 2016
Issue Published Current Pharmaceutical Design Vol.22 Issue 40
Issue Published Current Pharmaceutical Design Vol.22 Issue 40
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Issue Published Current Pharmaceutical Design Vol.22 Issue 39
Issue Published Current Pharmaceutical Design Vol.22 Issue 39
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Wednesday, December 14, 2016
Podcast for (From Small to Powerful: The Fragments Universe and its "Chem-Appeal." by Dr. Tabrarrini)
Podcast for (From Small to Powerful: The Fragments Universe and its "Chem-Appeal." by Dr. Tabrarrini)
...
Thursday, December 8, 2016
Free Online Issue of Current Pharmaceutical Design
Free Online Issue of Current Pharmaceutical Design
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Sunday, December 4, 2016
New Issue Published Current Pharmaceutical Design Vol. 22 Issue 38
New Issue Published Current Pharmaceutical Design Vol. 22 Issue 38
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Tuesday, November 29, 2016
Highlighted Article: Insulin Resistance and Polycystic Ovary Syndrome
Highlighted Article: Insulin Resistance and Polycystic Ovary Syndrome
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Wednesday, November 23, 2016
Issue Published Current Pharmaceutical Design Vol.22 Issue 37
Issue Published Current Pharmaceutical Design Vol.22 Issue 37
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Monday, November 21, 2016
Issue Published Current Pharmaceutical Design Vol. 22 Issue 36
Issue Published Current Pharmaceutical Design Vol. 22 Issue 36
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Tuesday, November 8, 2016
Call For Paper
Bentham Science Publishers would like to invite you to submit your research paper for publishing in the Journal of
Current Pharmaceutical Design
...
Tuesday, November 1, 2016
Highlighted Article: Antiepileptic Drugs Based on the α-Substituted Amide Group Pharmacophore: From Chemical Crystallography to Molecular Pharmaceutics
Antiepileptic Drugs Based on the α-Substituted Amide Group Pharmacophore: From Chemical Crystallography to Molecular Pharmaceutics
Author(s):
Arcadius V. Krivoshein Pages 5029 - 5040 ( 12 )
Abstract:
The antiepileptic activity of α-substituted acetamides, lactams, and cyclic imides has been known for over six decades. We recently proposed an α-substituted amide group as the minimum pharmacophore responsible for inhibition of neuronal...
Sunday, October 23, 2016
Most Cited Article: The Role of ABC Transporters in Protecting Cells from Bilirubin Toxicity
The Role of ABC Transporters in Protecting Cells from Bilirubin
Toxicity
Author(s):
C. Bellarosa, G. Bortolussi and C.
TiribelliPages 2884-2892 (9)
Abstract:
The ATP-Binding Cassette (ABC) superfamily is the largest transporter family
known to translocate a wide variety of exogenous and endogenous substrates
across cell membranes. In this chapter we review the potential role of three
ABC proteins in the transport of unconjugated...
Tuesday, October 18, 2016
AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
AFM-Based Single Molecule Techniques: Unraveling the Amyloid Pathogenic Species
Author(s):
Francesco Simone Ruggeri, Johnny Habchi, Andrea Cerreta and Giovanni DietlerPages 3950-3970 (21)
Abstract:
Background: A wide class of human diseases and neurodegenerative disorders, such as Alzheimer’s disease, is due to the failure of a specific peptide or protein to keep its native functional conformational state and to undergo a conformational change...
Sunday, October 9, 2016
The Microbial Quality Aspects and Decontamination Approaches for the Herbal Medicinal Plants and Products: An in-Depth Review
The Microbial Quality Aspects and Decontamination Approaches for the Herbal Medicinal Plants and Products: An in-Depth Review
[ Vol. 22 , Issue. 27 ]
Author(s):
Daniela Dal Molim Ghisleni, Marina de Souza Braga, Irene Satiko Kikuchi, Mirela Braşoveanu, Monica R. Nemţanu, Kamal Dua and Terezinha de Jesus Andreoli PintoPages 4264-4287 (24)
Abstract:
Background: The present review article provides an overview of the published literature...
Wednesday, October 5, 2016
Upcoming Thematic Issue – Cardiovascular Prevention: Can We Do Any Better
courtesy by Bentham Insig...
New Issue ::: Current Pharmaceutical Design , 22 Issue 27
Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.
Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug...
Current Pharmaceutical Design , 22 Issue 26
Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field.
Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug...
Friday, June 24, 2016
Lipid-Based Nanocarriers for RNA Delivery
Author(s):
Hui Yi Xue, Pengbo Guo, Wu-Cheng Wen and Ho Lun WongPages 3140-3147 (8)
Abstract:
RNA-interference (RNAi) agents such as small-interfering RNA (siRNA) and micro-RNA (miRNA) have strong potential as therapeutic agents for the treatment of a broad range of diseases such as malignancies, infections, autoimmune diseases and neurological diseases that are associated with undesirable gene expression. In recent years, several clinical trials...
Recent advances in the fundamental understanding of adhesive mixtures for inhalation
Author(s):
Floris Grasmeijer, Niels Grasmeijer, Paul Hagedoorn, Henderik Willem Frijlink and Anne Haaije de BoerPages 5900-5914 (15)
Abstract:
Adhesive mixtures for inhalation are the most widely used type of formulation in dry powder inhalation products. Although they have been the subject of active research, the relationships between properties of the starting materials, the mixing and dispersion processes, and the dispersion performance of...
Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier
Author(s):
David S. Hersh, Aniket S. Wadajkar, Nathan B. Roberts, Jimena G. Perez, Nina P. Connolly, Victor Frenkel, Jeffrey A. Winkles, Graeme F. Woodworth and Anthony J. KimPages 1177-1193 (17)
Abstract:
The blood-brain barrier (BBB) poses a unique challenge for drug delivery to the central nervous system (CNS). The BBB consists of a continuous layer of specialized endothelial cells linked together by tight junctions, pericytes, nonfenestrated...
The Therapeutic Aspects of the Endocannabinoid System (ECS) for Cancer and their Development: From Nature to Laboratory
Author(s):
Mohammed I. Khan, Anna A. Sobocińska, Anna M. Czarnecka, Magdalena Król, Bruno Botta and Cezary SzczylikPages 1756-1766 (11)
Abstract:
The endocannabinoid system (ECS) is a group of neuromodulatory lipids and their receptors, which are widely distributed in mammalian tissues. ECS regulates various cardiovascular, nervous, and immune system functions inside cells. In recent years, there has been a growing body of evidence for the use...
Therapeutic Targets for Management of Periodontitis and Diabetes
Author(s):
Corneliu Sima and Thomas E. Van DykePages 2216-2237 (22)
Abstract:
The increasing incidence of diabetes mellitus (DM) and chronic periodontitis (CP) worldwide imposes a rethinking of individualized therapy for patients with both conditions. Central to bidirectional links between DM and CP is deregulated systemic inflammation and dysfunctional immune responses to altered-self and non-self. Control of blood glucose levels and metabolic...
